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温肾助阳作用较强，外用治白癜风多用生品
引药入肾，温肾纳气、固精缩尿之力增强，并缓和辛燥之性
煎服6–10g。外用适量，酒浸涂患处。
For educational reference only — not medical advice.
补骨脂含呋喃香豆素（补骨脂素、异补骨脂素）、补骨脂酚及黄酮类，具有光敏、补肾助阳、抗骨质疏松及色素沉着作用；近年临床报告显示其内服可能引起药物性肝损伤。
Psoraleae Fructus contains furanocoumarins (psoralen, isopsoralen), bakuchiol, and flavonoids, with photosensitizing, kidney yang-tonifying, antiosteoporotic, and pro-pigmentation activity; drug-induced liver injury has been reported with internal use.
Bensky 记载补骨脂素为经典的 PUVA 光敏剂，国际上长期用于白癜风和银屑病的治疗。
Bensky documents psoralen as a classic PUVA photosensitizer, used internationally for vitiligo and psoriasis.
Brinker 总结了多个国家关于补骨脂（包括中成药壮骨关节丸等）引起药物性肝损伤的病例报告，建议避免长期高剂量使用并监测肝功能。
Brinker summarizes case reports from multiple countries of drug-induced liver injury associated with Psoralea (including proprietary products such as Zhuang Gu Guan Jie Wan), advising against prolonged high-dose use and recommending liver monitoring.
陈氏药理学提醒使用补骨脂制剂后应避免过度日晒，以防光敏性皮炎。
Chen & Chen advise avoidance of excessive sun exposure after use to prevent photosensitizing dermatitis.
This section is provided for academic reference only and does not constitute medical advice.
阴虚火旺、大便秘结者忌服。本品性温燥，阴虚有热者不宜。外用或内服后需避光，以防光敏性皮炎。现代报道有肝毒性，不宜长期或大剂量服用。
含补骨脂素等呋喃香豆素类成分，具光敏性，服用或外用后须避免阳光暴晒，以防光敏性皮炎、色素沉着。现代有肝损害报道，肝功能异常者忌用，不宜长期超量服用。
补骨脂，治肾泄、通命门、暖丹田、敛精神。能使心包之火与命门之火相通，故元阳坚固，骨髓充实，涩以固脱也。
补骨脂主五劳七伤，风虚冷，骨髓伤败，肾冷精流。又主妇人血气堕胎。
@misc{bencaodian-bu-gu-zhi,
author = {{Bencaodian Editorial}},
title = {Bǔ Gǔ Zhī 补骨脂 (Psoralea Fruit) — Psoraleae Fructus},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/herbs/bu-gu-zhi},
urldate = {2026-04-09},
note = {CC BY-SA 4.0}
}