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The dried root of Stephania tetrandra (Menispermaceae). Enters the Bladder and Lung channels. Bitter, pungent, and cold, it dispels wind-dampness and alleviates pain while promoting urination and reducing edema. Particularly suitable for wind-damp-heat impediment with red, swollen, hot, painful joints and for wind-water or skin-water edema. Han fang ji and mu fang ji must be distinguished, and Aristolochia fangchi must be absolutely avoided due to nephrotoxicity.
祛风湿，利水消肿
宜用粉防己（汉防己，Stephania tetrandra），利水消肿力胜；木防己（青风藤类）偏于祛风通络止痛。
Reference range for non-pregnant adults. Not a personalized prescription. Pregnancy, lactation, and pediatric use require specialist supervision.
Protective guidance only — when to avoid or use with caution. This block deliberately omits pregnancy, lactation, and pediatric dosing: any such use must be managed by a qualified TCM practitioner or appropriate specialist.
食欲不振及阴虚无湿热者忌服。脾胃虚寒者慎用。严禁误用广防己（马兜铃科，含马兜铃酸）以防肾毒。
本品所指为粉防己（汉防己，Stephaniae Tetrandrae Radix），非马兜铃科广防己（Aristolochia fangchi，含肾毒性马兜铃酸，已在多国禁用）。处方调剂须严格区分品种。
味辛，平。主风寒温疟，热气诸痫，除邪，利大小便。
中品
@misc{bencaodian-fang-ji,
author = {{Bencaodian Editorial}},
title = {Fáng Jǐ 防己 (Stephania Root) — Stephaniae Tetrandrae Radix},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/herbs/fang-ji},
urldate = {2026-04-17},
note = {CC BY-SA 4.0}
}© Bencaodian Editorial · Licensed under CC BY-SA 4.0
粉防己（汉防己，Stephania tetrandra）主含双苄基异喹啉生物碱（粉防己碱、防己诺林碱），药理示其钙通道阻滞、降压、抗炎、抗纤维化与抗肿瘤作用。
Fangji (Stephania tetrandra) contains bisbenzylisoquinoline alkaloids (tetrandrine, fangchinoline); pharmacology shows calcium channel blockade, antihypertensive, anti-inflammatory, antifibrotic and antitumor activity.
《中国药典》仅收载粉防己（Stephania tetrandra），严禁使用含马兜铃酸的广防己（Aristolochia fangchi）。
Chinese Pharmacopoeia lists only Stephania tetrandra; Aristolochia fangchi (containing aristolochic acid) is prohibited.
WHO 与多国监管机构均警示广防己类马兜铃酸肾毒性及致癌风险。
WHO and regulators warn of aristolochic acid nephrotoxicity and carcinogenicity from Aristolochia species.
应严格区分粉防己与广防己以避免误用。
Strict botanical identification is required to avoid substitution with Aristolochia species.
This section is provided for academic reference only and does not constitute medical advice.