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多外用，内服少用，刺激性较强
降低毒性与燥烈之性，多用于内服
内服用量宜小，一般2–5g；外用适量。因有小毒，不宜久服。
For educational reference only — not medical advice.
吴茱萸主含吴茱萸碱、吴茱萸次碱等吲哚喹唑啉生物碱，具有镇痛、止呕、血管舒张及抗溃疡作用。
Evodia fruit contains indoloquinazoline alkaloids (evodiamine, rutaecarpine) with analgesic, antiemetic, vasorelaxant and anti-ulcer effects.
散寒止痛、疏肝下气、助阳止泻，为吴茱萸汤君药；小毒，不宜过量久服。
Disperses cold, moves Liver qi downward, warms yang and stops diarrhea; sovereign herb of Wu Zhu Yu Tang; slightly toxic, should not be overdosed or used long-term.
高剂量或长期使用有肝毒性报告；吴茱萸碱可影响多种 CYP 酶和 P-糖蛋白。
Hepatotoxicity has been reported with high-dose or prolonged use; evodiamine modulates multiple CYP enzymes and P-glycoprotein.
《中国药典》以吴茱萸碱和吴茱萸次碱总量作含量测定指标。
The Chinese Pharmacopoeia uses combined evodiamine plus rutaecarpine as the assay marker.
This section is provided for academic reference only and does not constitute medical advice.
本品辛热燥烈，有小毒，不宜多服久服。阴虚火旺者忌用。孕妇慎用。
本品有小毒，内服不宜多量久服，过量可致视力障碍、错觉、毛发脱落及腹痛等反应。阴虚火旺者忌用。孕妇慎用。
食谷欲呕者，属阳明也，吴茱萸汤主之。
@misc{bencaodian-wu-zhu-yu,
author = {{Bencaodian Editorial}},
title = {Wú Zhū Yú 吴茱萸 (Evodia Fruit) — Evodiae Fructus},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/herbs/wu-zhu-yu},
urldate = {2026-04-09},
note = {CC BY-SA 4.0}
}