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Cinnabar (Cinnabaris), a sulfide mineral primarily composed of mercuric sulfide (HgS). Enters the Heart channel. Sweet, slightly cool, and heavy, it is the representative heavy sedative for clearing the Heart and suppressing fright. However, because it contains mercury and is toxic, it must be processed by the water-flying method and must NEVER be calcined or decocted. Modern use calls for minimal dosage and short courses.
去除杂质（游离汞），降低毒性
研末冲服每次0.1–0.5g，或入丸散。绝不可火煅或入煎剂。外用适量。
Reference range for non-pregnant adults. Not a personalized prescription. Pregnancy, lactation, and pediatric use require specialist supervision.
Protective guidance only — when to avoid or use with caution. This block deliberately omits pregnancy, lactation, and pediatric dosing: any such use must be managed by a qualified TCM practitioner or appropriate specialist.
本品为硫化汞（HgS），含汞，有毒。不可火煅或入煎剂（加热释放游离汞）。不宜过量或久服。肝肾功能不全者禁用。孕妇禁用。婴幼儿慎用。
严重警告：本品为硫化汞（HgS），含汞元素。硫化汞本身溶解度极低，毒性较游离汞小，但以下情况可致严重汞中毒：(1) 火煅或入煎剂（加热释放游离汞蒸气）；(2) 长期服用（汞蓄积）；(3) 掺有游离汞的劣质品。汞中毒可损伤中枢神经系统、肾脏和消化系统。须经水飞法炮制以去除游离汞。现代药理建议尽量减少使用，多数含朱砂中成药（朱砂安神丸、安宫牛黄丸等）已受到更严格的安全审查。肝肾功能不全者绝对禁用。
味甘，微寒。主身体五脏百病，养精神，安魂魄，益气明目，杀精魅邪恶鬼。久服通神明不老。
上品
@misc{bencaodian-zhu-sha,
author = {{Bencaodian Editorial}},
title = {Zhū Shā 朱砂 (Cinnabar) — Cinnabaris},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/herbs/zhu-sha},
urldate = {2026-04-16},
note = {CC BY-SA 4.0}
}© Bencaodian Editorial · Licensed under CC BY-SA 4.0
朱砂主含硫化汞，具有镇静安神作用；但汞元素有神经毒性和肾毒性，须严格控制用量和炮制方法。
Cinnabar consists mainly of mercuric sulfide with sedative properties; however, mercury is neurotoxic and nephrotoxic, requiring strict dosage control and proper processing.
《中国药典》严格限定朱砂含量、游离汞限量及水飞法炮制要求。
Chinese Pharmacopoeia strictly regulates cinnabar content, free mercury limits, and water-flying processing requirements.
This section is provided for academic reference only and does not constitute medical advice.