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Formula和解剂· 调和肝脾

四逆散

Sì Nì Sǎn

Frigid Extremities Powder

From the Shang Han Lun, this treats counterflow cold of the extremities due to yang constraint (not yang vacuity). Chai Hu raises and disperses to vent pathogens, Bai Shao constrains yin and harmonizes the nutritive, Zhi Shi moves qi and breaks binds, and Gan Cao harmonizes — together they course the Liver, regulate the Spleen, and free constrained yang. The foundational formula for Liver-Spleen harmonization.

Source《伤寒论》

Treatment Principle

透邪解郁，疏肝理脾

Vent pathogens and resolve constraint, course the Liver and regulate the Spleen

Composition · 组成

Herb	Role	Dosage	Notes
柴胡Chái Hú	君Sovereign	6g	透邪解郁，疏肝升阳，为君药
白芍Bái Sháo	臣Minister	9g	养血柔肝，敛阴和营
枳实Zhǐ Shí	佐Assistant	6g	理气解郁，泻脾气之壅
甘草Gān Cǎo	使Courier	6g	调和诸药

Preparation · 煎服法

研细末，白饮和服。今多改为汤剂。

Draft

PractitionerPatientDate

四逆散Sì Nì Sǎn

Frigid Extremities Powder

Herb	Pinyin	Role	Dose
柴胡	Chái Hú	Jun (Sovereign)	6g
白芍	Bái Sháo	Chen (Minister)	9g
枳实	Zhǐ Shí	Zuo (Assistant)	6g
甘草	Gān Cǎo	Shi (Courier)	6g

Preparation: 研细末，白饮和服。今多改为汤剂。

This prescription is provided only by the dispensing TCM practitioner. Take as directed; do not modify the dose or share it. If you experience any adverse effect, stop immediately and contact your practitioner. The content of this platform is educational reference, not medical advice.
Bencao Dian · https://bencaodian.org · CC BY-SA 4.0

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Cite this entry

@misc{bencaodian-si-ni-san,
  author       = {{Bencaodian Editorial}},
  title        = {Sì Nì Sǎn 四逆散 (Frigid Extremities Powder)},
  year         = {2026},
  howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
  url          = {https://bencaodian.org/en/formulas/si-ni-san},
  urldate      = {2026-04-16},
  note         = {CC BY-SA 4.0}
}

Permalink is fixed

Herb

Role

Dosage

Notes

透邪解郁，疏肝升阳，为君药

养血柔肝，敛阴和营

理气解郁，泻脾气之壅

调和诸药

Herb

Pinyin

Role

Dose

柴胡

Chái Hú

Jun (Sovereign)

白芍

Bái Sháo

Chen (Minister)

枳实

Zhǐ Shí

Zuo (Assistant)

甘草

Gān Cǎo

Shi (Courier)

@misc{bencaodian-si-ni-san, author = {{Bencaodian Editorial}}, title = {Sì Nì Sǎn 四逆散 (Frigid Extremities Powder)}, year = {2026}, howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine}, url = {https://bencaodian.org/en/formulas/si-ni-san}, urldate = {2026-04-16}, note = {CC BY-SA 4.0} }