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The dried seed kernel of Myristica fragrans (Myristicaceae). Enters the Spleen, Stomach, and Large Intestine channels. Pungent, warm, and aromatic, it warms the middle, moves qi, binds the intestines, and stops diarrhea. It is the key herb for Spleen-Kidney vacuity-cold chronic diarrhea and dawn diarrhea, combined with bu gu zhi, wu wei zi, and wu zhu yu in Si Shen Wan. It must be processed by baking (wei rou dou kou) to reduce toxicity.
煨制可去除大部分挥发油，减轻刺激性与毒性，增强涩肠止泻之功
煎服3–9g，入丸散每次0.5–1g。必须煨用，去油后入药。
Reference range for non-pregnant adults. Not a personalized prescription. Pregnancy, lactation, and pediatric use require specialist supervision.
Protective guidance only — when to avoid or use with caution. This block deliberately omits pregnancy, lactation, and pediatric dosing: any such use must be managed by a qualified TCM practitioner or appropriate specialist.
湿热泻痢、肠胃实热、阴虚火旺者忌服。生肉豆蔻含挥发油（肉豆蔻醚等），过量服用可致中毒，必须煨制后入药；不可生服，不可超量。
生肉豆蔻含肉豆蔻醚（myristicin）等挥发油成分，过量可致幻、恶心、呕吐、心动过速，甚至昏迷。临床须用煨制品，控制剂量在常用范围内，严禁生用或大剂量服用。孕妇慎用。
肉豆蔻，辛，温，无毒。暖脾胃，固大肠，止虚泻冷痢、心腹胀痛、宿食不消、小儿乳霍。
@misc{bencaodian-rou-dou-kou,
author = {{Bencaodian Editorial}},
title = {Ròu Dòu Kòu 肉豆蔻 (Nutmeg) — Myristicae Semen},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/herbs/rou-dou-kou},
urldate = {2026-04-17},
note = {CC BY-SA 4.0}
}© Bencaodian Editorial · Licensed under CC BY-SA 4.0
肉豆蔻含挥发油（肉豆蔻醚、榄香素）及固定油，现代研究报道抗腹泻、抗菌、抗炎及中枢作用；过量有神经毒性及幻觉风险，故多煨用并严格控制剂量。
Nutmeg (Myristica) contains volatile oil rich in myristicin and elemicin plus a fixed oil (trimyristin), with antidiarrheal, antimicrobial, anti-inflammatory, and central effects in preclinical work. Overdose risks neurotoxicity and hallucinations, so it is usually dry-roasted (wei) and dosed conservatively.
《中药学》（Bensky）强调肉豆蔻须煨去油方可内服以减毒，每日 3–6 g。
Bensky emphasizes that nutmeg should be dry-roasted to remove repletion oil before oral use, daily dose 3–6 g.
Brinker 记载肉豆蔻醚具单胺氧化酶抑制活性，大剂量（>5 g 粉末）可致幻觉、心动过速及肝毒性。
Brinker records that myristicin has MAO-inhibiting activity; large doses (>5 g powder) can cause hallucinations, tachycardia, and hepatotoxicity.
This section is provided for academic reference only and does not constitute medical advice.