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The dried ripe fruit of Schisandra chinensis (Schisandraceae). Enters the Lung, Heart, and Kidney channels. Sour and sweet with warm nature, its skin and flesh are sweet-sour while the kernel is pungent-bitter, embodying all five flavors though sourness predominates. It is the essential herb for astringent-securing the Lung and enriching the Kidney, featured in Sheng Mai San.
敛肺止咳、生津敛汗之力较强
增强酸涩收敛之性，涩精止泻
补益作用增强，缓和酸性
煎服2–6g；研末服每次1–3g；敛肺止咳宜生用，补肾涩精宜蜜炙或醋炙
Reference range for non-pregnant adults. Not a personalized prescription. Pregnancy, lactation, and pediatric use require specialist supervision.
Documented interactions exist with the following Western drug classes. Click to view mechanism, severity, and clinical recommendations.
Protective guidance only — when to avoid or use with caution. This block deliberately omits pregnancy, lactation, and pediatric dosing: any such use must be managed by a qualified TCM practitioner or appropriate specialist.
外有表邪、内有实热、咳嗽初起、麻疹初发者均忌用。
现代研究示有降转氨酶作用，但过量可致胃肠刺激、反酸。表邪未解者服用易留邪。
味酸，温。主益气，咳逆上气，劳伤羸瘦，补不足，强阴，益男子精。
上品
@misc{bencaodian-wu-wei-zi,
author = {{Bencaodian Editorial}},
title = {Wǔ Wèi Zǐ 五味子 (Schisandra Fruit) — Schisandrae Chinensis Fructus},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/herbs/wu-wei-zi},
urldate = {2026-04-17},
note = {CC BY-SA 4.0}
}© Bencaodian Editorial · Licensed under CC BY-SA 4.0
五味子主含联苯环辛烯型木脂素（五味子素甲乙丙、戈米辛等），具有保肝降酶、镇静、适应原样及抗氧化作用。
Schisandra fruit contains dibenzocyclooctadiene lignans (schisandrins A/B/C, gomisins) with hepatoprotective, transaminase-lowering, sedative, adaptogenic and antioxidant effects.
联苯双酯（双环醇）为五味子丙素的合成衍生物，收录于《中国药典》用于保肝降酶。
Bifendate/bicyclol, a synthetic derivative of schisandrin C, is listed in the Chinese Pharmacopoeia as a hepatoprotective agent.
可诱导 CYP3A4 代谢，可能降低他克莫司、环孢素等免疫抑制剂血药浓度。
Induces CYP3A4; may reduce plasma levels of tacrolimus, cyclosporine and related immunosuppressants.
《中国药典》以五味子醇甲（五味子素甲）为含量测定指标，不得少于0.40%。
The Chinese Pharmacopoeia uses schisandrin (schizandrin) as the assay marker, requiring not less than 0.40%.
This section is provided for academic reference only and does not constitute medical advice.