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清热泻火之力较强，用于气分实热
引药下行，滋阴降火力胜，善治下焦阴虚火旺
煎服6–12g；清热泻火宜生用，滋阴降火宜盐水炒
For educational reference only — not medical advice.
知母含知母皂苷及芒果苷等成分，具有解热、降血糖、抗炎、抗菌及神经保护作用，为清热泻火、滋阴润燥之药理依据。
Anemarrhena rhizome contains timosaponins and mangiferin with antipyretic, hypoglycemic, anti-inflammatory, antimicrobial and neuroprotective effects, underlying its heat-clearing, fire-draining and yin-nourishing actions.
Bensky 将知母配石膏清气分实热，配黄柏滋肾降火。
Bensky pairs Zhi Mu with Shi Gao to clear qi-level excess heat and with Huang Bai to nourish kidney and drain fire.
Chen & Chen 引述知母皂苷 B-II 在阿尔茨海默动物模型中显示神经保护作用。
Chen & Chen cite timosaponin B-II showing neuroprotection in Alzheimer's animal models.
This section is provided for academic reference only and does not constitute medical advice.
脾胃虚寒、大便溏泄者忌用。
性寒质润，脾虚便溏者忌用。久服大量可碍脾助湿。
味苦，寒。主消渴热中，除邪气，肢体浮肿，下水，补不足，益气。
中品
@misc{bencaodian-zhi-mu,
author = {{Bencaodian Editorial}},
title = {Zhī Mǔ 知母 (Anemarrhena Rhizome) — Anemarrhenae Rhizoma},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/herbs/zhi-mu},
urldate = {2026-04-09},
note = {CC BY-SA 4.0}
}