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《伤寒论》厥阴篇温经散寒、养血通脉之代表方。主治血虚受寒、寒凝经脉之手足厥寒、舌淡苔白、脉细欲绝，或兼腰股腿足冷痛、妇女经行腹痛、寒疝等。与四逆汤之回阳救逆不同，本方重在温经养血通脉，故不用姜附而用当归、桂枝、细辛。加吴茱萸、生姜即当归四逆加吴茱萸生姜汤。
| 本草 | 君臣佐使 | 剂量 | 说明 |
|---|---|---|---|
| 当归Dāng Guī | 君Sovereign | 9g | 养血和营，活血通脉，为君 |
| 桂枝Guì Zhī | 臣Minister | 9g | 温经散寒，温通血脉 |
| 白芍Bái Sháo | 臣Minister | 9g | 养血和营，与当归同补营血 |
| 细辛Xì Xīn | 佐Assistant | 3g | 辛温散寒，通达阳气，助桂枝温散血分寒邪 |
| 大枣Dà Zǎo | 佐Assistant | 8枚 | 甘温益气养血，与甘草同补脾气以助生血 |
| 甘草Gān Cǎo | 使Envoy | 6g | 益气补中，调和诸药；用炙甘草 |
上七味，以水八升，煮取三升，去滓，温服一升，日三服。
@misc{bencaodian-dang-gui-si-ni-tang,
author = {{Bencaodian Editorial}},
title = {Dāng Guī Sì Nì Tāng 当归四逆汤 (Tangkuei Decoction for Frigid Extremities)},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/zh/formulas/dang-gui-si-ni-tang},
urldate = {2026-04-09},
note = {CC BY-SA 4.0}
}