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Formula补益剂· 补阴

大补阴丸

Dà Bǔ Yīn Wán

Great Yin Supplementation Pill

The representative formula for yin vacuity with effulgent fire. Heavy yin-enriching ingredients strengthen water to control fire, assisted by bitter-cold fire-draining medicinals to directly quench its force. The use of pork spinal marrow in the pill base underscores its essence-replenishing, marrow-benefiting intention.

Source《丹溪心法》卷一

Treatment Principle

滋阴降火

Enrich yin and downbear fire

Composition · 组成

Herb	Role	Dosage	Notes
熟地黄Shú Dì Huáng	君Sovereign	18g	滋阴填精，补肾水之不足
龟甲胶Guī Jiǎ Jiāo	君Sovereign	18g	滋阴潜阳，壮水以制火
黄柏Huáng Bǎi	臣Minister	12g	泻相火，清下焦湿热
知母Zhī Mǔ	臣Minister	12g	滋阴清热，助黄柏泻火

Modifications · 加减

咳血
+ 青蒿、侧柏叶
阴虚火旺灼伤肺络
遗精
+ 山茱萸、芡实
相火妄动

Preparation · 煎服法

上药研末，猪脊髓蒸熟，炼蜜为丸，每服9g，每日2次，淡盐汤送服。

Editor-reviewed· 2026-04-16

PractitionerPatientDate

大补阴丸Dà Bǔ Yīn Wán

Great Yin Supplementation Pill

Herb	Pinyin	Role	Dose
熟地黄	Shú Dì Huáng	Jun (Sovereign)	18g
龟甲胶	Guī Jiǎ Jiāo	Jun (Sovereign)	18g
黄柏	Huáng Bǎi	Chen (Minister)	12g
知母	Zhī Mǔ	Chen (Minister)	12g

Preparation: 上药研末，猪脊髓蒸熟，炼蜜为丸，每服9g，每日2次，淡盐汤送服。

This prescription is provided only by the dispensing TCM practitioner. Take as directed; do not modify the dose or share it. If you experience any adverse effect, stop immediately and contact your practitioner. The content of this platform is educational reference, not medical advice.
Bencao Dian · https://bencaodian.org · CC BY-SA 4.0

Permalink · CC BY-SA 4.0

Cite this entry

@misc{bencaodian-da-bu-yin-wan,
  author       = {{Bencaodian Editorial}},
  title        = {Dà Bǔ Yīn Wán 大补阴丸 (Great Yin Supplementation Pill)},
  year         = {2026},
  howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
  url          = {https://bencaodian.org/en/formulas/da-bu-yin-wan},
  urldate      = {2026-04-17},
  note         = {CC BY-SA 4.0}
}

Permalink is fixed

Herb

Role

Dosage

Notes

熟地黄Shú Dì Huáng

君Sovereign

18g

滋阴填精，补肾水之不足

龟甲胶Guī Jiǎ Jiāo

君Sovereign

18g

滋阴潜阳，壮水以制火

黄柏Huáng Bǎi

臣Minister

12g

泻相火，清下焦湿热

知母Zhī Mǔ

臣Minister

12g

滋阴清热，助黄柏泻火

Herb

Pinyin

Role

Dose

熟地黄

Shú Dì Huáng

Jun (Sovereign)

18g

龟甲胶

Guī Jiǎ Jiāo

Jun (Sovereign)

18g

黄柏

Huáng Bǎi

Chen (Minister)

12g

知母

Zhī Mǔ

Chen (Minister)

12g

@misc{bencaodian-da-bu-yin-wan, author = {{Bencaodian Editorial}}, title = {Dà Bǔ Yīn Wán 大补阴丸 (Great Yin Supplementation Pill)}, year = {2026}, howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine}, url = {https://bencaodian.org/en/formulas/da-bu-yin-wan}, urldate = {2026-04-17}, note = {CC BY-SA 4.0} }