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清热燥湿，泻火解毒之力最强，多用于湿热泻痢、高热神昏
缓和苦寒之性，和胃止呕，善治胃热呕吐
借酒上行，善清头目之火，治目赤肿痛、口舌生疮
内服煎汤一般2–5g；清心、清胃可用3–6g；外用适量，研末调敷
For educational reference only — not medical advice.
黄连主含异喹啉生物碱（以小檗碱为代表），具广谱抗菌、抗炎、降血糖、调血脂及抗心律失常等现代药理作用。
Coptis contains isoquinoline alkaloids led by berberine, with broad-spectrum antimicrobial, anti-inflammatory, hypoglycemic, lipid-lowering, and antiarrhythmic pharmacological activity.
传统视黄连为苦寒清热燥湿要药，现代研究证实其生物碱抗菌活性。
Traditionally the premier bitter-cold herb for damp-heat; modern studies confirm alkaloid-based antimicrobial action.
小檗碱对痢疾杆菌、金黄色葡萄球菌、幽门螺杆菌等均有抑制作用。
Berberine inhibits Shigella, Staphylococcus aureus, and Helicobacter pylori among others.
孕妇及新生儿禁用——小檗碱可置换胆红素诱发核黄疸；并注意其 CYP3A4/P-gp 相互作用。
Contraindicated in pregnancy and neonates — berberine displaces bilirubin and may precipitate kernicterus; caution with CYP3A4/P-gp interactions.
《中国药典》以小檗碱含量（不少于 5.5%）为质量控制指标。
Chinese Pharmacopoeia specifies berberine content (≥5.5%) as the quality marker.
This section is provided for academic reference only and does not constitute medical advice.
脾胃虚寒者忌用。苦寒伤胃，易败胃气，不宜久服大量。阴虚津伤者慎用。
本品大苦大寒，过用或久服易伤脾胃阳气。含小檗碱，新生儿及G6PD缺乏者慎用，可诱发溶血。不宜与猪肉同食（古训）。
味苦，寒。主热气目痛，眦伤泣出，明目，肠澼腹痛下痢，妇人阴中肿痛。久服令人不忘。
上品
@misc{bencaodian-huang-lian,
author = {{Bencaodian Editorial}},
title = {Huáng Lián 黄连 (Coptis Rhizome) — Coptidis Rhizoma},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/herbs/huang-lian},
urldate = {2026-04-09},
note = {CC BY-SA 4.0}
}