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New to this? Read about the Sovereign-Minister-Assistant-Courier hierarchy
Zhang Zhongjing's formula from the Shang Han Lun jue yin chapter (line 338), serving as both an antiparasitic and a representative formula for jue yin cold-heat complex patterns. It treats roundworm reversal (hui jue) with paroxysmal epigastric pain, vomiting after eating, and vomiting of worms, as well as chronic diarrhea and dysentery of the cold-heat complex type. The formula combines sour (wu mei), pungent (xi xin, gui zhi, fu zi, gan jiang), and bitter (huang lian, huang bai) with qi and blood supplementation.
Source《伤寒论》辨厥阴病脉证并治| Herb | Role | Dosage | Notes |
|---|---|---|---|
| 乌梅Wū Méi | 君Sovereign | 300 pieces | 味极酸,蛔得酸则静,为君药 |
| 细辛Xì Xīn | 臣Minister | 6g | 辛温散寒,蛔得辛则伏 |
| 干姜Gān Jiāng | 臣Minister | 10g | 温中散寒,温脏以安蛔 |
| 附子Fù Zǐ | 臣Minister | 6g | 温肾暖脾,助干姜温脏 |
| 桂枝Guì Zhī | 臣Minister | 6g | 通阳散寒,温经通脉 |
| 黄连Huáng Lián | 佐Assistant | 16g | 苦寒清热,蛔得苦则下 |
| 黄柏Huáng Bǎi | 佐Assistant | 6g | 苦寒清热燥湿,与黄连同泄上热 |
| 人参Rén Shēn | 佐Assistant | 6g | 大补元气,以复下虚 |
| 当归Dāng Guī | 佐Assistant | 4g | 养血和血,合人参补气养血 |
异捣筛,合治之。以苦酒渍乌梅一宿,去核,蒸之五斗米下,饭熟捣成泥,和药令相得,内臼中,与蜜杵二千下,丸如梧桐子大。先食饮服十丸,日三服,稍加至二十丸。禁生冷、滑物、臭食等。
@misc{bencaodian-wu-mei-wan,
author = {{Bencaodian Editorial}},
title = {Wū Méi Wán 乌梅丸 (Mume Pill)},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/formulas/wu-mei-wan},
urldate = {2026-04-17},
note = {CC BY-SA 4.0}
}© Bencaodian Editorial · Licensed under CC BY-SA 4.0