Loading
New to this? Read about Four Natures & Five Flavors and Channel Tropism
The dried nearly ripe fruit of Evodia rutaecarpa, E. rutaecarpa var. officinalis, or E. rutaecarpa var. bodinieri (Rutaceae). Enters the Liver, Spleen, Stomach, and Kidney channels. Pungent, bitter, and hot, it is the key herb for jue yin headache and Liver-Stomach vacuity cold. Zhang Zhongjing's Wu Zhu Yu Tang is its representative formula, treating both vertex headache from jue yin cold and Stomach-cold vomiting.
多外用，内服少用，刺激性较强
降低毒性与燥烈之性，多用于内服
内服用量宜小，一般2–5g；外用适量。因有小毒，不宜久服。
Reference range for non-pregnant adults. Not a personalized prescription. Pregnancy, lactation, and pediatric use require specialist supervision.
Protective guidance only — when to avoid or use with caution. This block deliberately omits pregnancy, lactation, and pediatric dosing: any such use must be managed by a qualified TCM practitioner or appropriate specialist.
本品辛热燥烈，有小毒，不宜多服久服。阴虚火旺者忌用。孕妇慎用。
本品有小毒，内服不宜多量久服，过量可致视力障碍、错觉、毛发脱落及腹痛等反应。阴虚火旺者忌用。孕妇慎用。
食谷欲呕者，属阳明也，吴茱萸汤主之。
@misc{bencaodian-wu-zhu-yu,
author = {{Bencaodian Editorial}},
title = {Wú Zhū Yú 吴茱萸 (Evodia Fruit) — Evodiae Fructus},
year = {2026},
howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
url = {https://bencaodian.org/en/herbs/wu-zhu-yu},
urldate = {2026-04-17},
note = {CC BY-SA 4.0}
}© Bencaodian Editorial · Licensed under CC BY-SA 4.0
吴茱萸主含吴茱萸碱、吴茱萸次碱等吲哚喹唑啉生物碱，具有镇痛、止呕、血管舒张及抗溃疡作用。
Evodia fruit contains indoloquinazoline alkaloids (evodiamine, rutaecarpine) with analgesic, antiemetic, vasorelaxant and anti-ulcer effects.
散寒止痛、疏肝下气、助阳止泻，为吴茱萸汤君药；小毒，不宜过量久服。
Disperses cold, moves Liver qi downward, warms yang and stops diarrhea; sovereign herb of Wu Zhu Yu Tang; slightly toxic, should not be overdosed or used long-term.
高剂量或长期使用有肝毒性报告；吴茱萸碱可影响多种 CYP 酶和 P-糖蛋白。
Hepatotoxicity has been reported with high-dose or prolonged use; evodiamine modulates multiple CYP enzymes and P-glycoprotein.
《中国药典》以吴茱萸碱和吴茱萸次碱总量作含量测定指标。
The Chinese Pharmacopoeia uses combined evodiamine plus rutaecarpine as the assay marker.
This section is provided for academic reference only and does not constitute medical advice.