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Formula补益剂· 补阴

六味地黄丸

Liù Wèi Dì Huáng Wán

Six Ingredient Pill with Rehmannia

Created by Qian Yi in Xiao Er Yao Zheng Zhi Jue, this is the representative formula for Liver-Kidney yin vacuity. Composed of shu di huang, shan zhu yu, shan yao (three supplementing herbs) and ze xie, mu dan pi, fu ling (three draining herbs), its meticulously balanced 'three supplements and three drains' configuration established the paradigm for all subsequent Liver-Kidney yin-nourishing formulas.

Source《小儿药证直诀》

Treatment Principle

滋补肝肾

Enrich and tonify the Liver and Kidney

Composition · 组成

Herb	Role	Dosage	Notes
熟地黄Shú Dì Huáng	君Sovereign	24g	滋阴补肾，填精益髓，为君药
山茱萸Shān Zhū Yú	臣Minister	12g	补养肝肾，并能涩精
山药Shān Yào	臣Minister	12g	补益脾阴，亦能固肾
泽泻Zé Xiè	佐Assistant	9g	利湿泄浊，并制熟地之滋腻
牡丹皮Mǔ Dān Pí	佐Assistant	9g	清泄肝火，制山茱萸之温
茯苓Fú Líng	佐Assistant	9g	淡渗脾湿，助山药之健运

Treats Patterns · 主治证型

阴虚证

Yīn Xū Zhèng

Yin Vacuity Pattern

Preparation · 煎服法

原为蜜丸；现亦作汤剂或浓缩丸服用。

Editor-reviewed· 2026-04-17

PractitionerPatientDate

六味地黄丸Liù Wèi Dì Huáng Wán

Six Ingredient Pill with Rehmannia

Herb	Pinyin	Role	Dose
熟地黄	Shú Dì Huáng	Jun (Sovereign)	24g
山茱萸	Shān Zhū Yú	Chen (Minister)	12g
山药	Shān Yào	Chen (Minister)	12g
泽泻	Zé Xiè	Zuo (Assistant)	9g
牡丹皮	Mǔ Dān Pí	Zuo (Assistant)	9g
茯苓	Fú Líng	Zuo (Assistant)	9g

Preparation: 原为蜜丸；现亦作汤剂或浓缩丸服用。

This prescription is provided only by the dispensing TCM practitioner. Take as directed; do not modify the dose or share it. If you experience any adverse effect, stop immediately and contact your practitioner. The content of this platform is educational reference, not medical advice.
Bencao Dian · https://bencaodian.org · CC BY-SA 4.0

Permalink · CC BY-SA 4.0

Cite this entry

@misc{bencaodian-liu-wei-di-huang-wan,
  author       = {{Bencaodian Editorial}},
  title        = {Liù Wèi Dì Huáng Wán 六味地黄丸 (Six Ingredient Pill with Rehmannia)},
  year         = {2026},
  howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine},
  url          = {https://bencaodian.org/en/formulas/liu-wei-di-huang-wan},
  urldate      = {2026-04-17},
  note         = {CC BY-SA 4.0}
}

Permalink is fixed

Herb

Role

Dosage

Notes

熟地黄Shú Dì Huáng

君Sovereign

24g

滋阴补肾，填精益髓，为君药

山茱萸Shān Zhū Yú

臣Minister

12g

补养肝肾，并能涩精

山药Shān Yào

臣Minister

12g

补益脾阴，亦能固肾

利湿泄浊，并制熟地之滋腻

清泄肝火，制山茱萸之温

淡渗脾湿，助山药之健运

Herb

Pinyin

Role

Dose

熟地黄

Shú Dì Huáng

Jun (Sovereign)

24g

山茱萸

Shān Zhū Yú

Chen (Minister)

12g

山药

Shān Yào

Chen (Minister)

12g

泽泻

Zé Xiè

Zuo (Assistant)

牡丹皮

Mǔ Dān Pí

Zuo (Assistant)

茯苓

Fú Líng

Zuo (Assistant)

@misc{bencaodian-liu-wei-di-huang-wan, author = {{Bencaodian Editorial}}, title = {Liù Wèi Dì Huáng Wán 六味地黄丸 (Six Ingredient Pill with Rehmannia)}, year = {2026}, howpublished = {Bencao Dian: A Bilingual Knowledge Graph of Traditional Chinese Medicine}, url = {https://bencaodian.org/en/formulas/liu-wei-di-huang-wan}, urldate = {2026-04-17}, note = {CC BY-SA 4.0} }